富含植物雌激素的补充剂与乳腺癌之间的关系:沙特阿拉伯的一个多中心病例控制研究
Sahar M Alnefaie1, Nawaf M Alwagdani2, Rashed A Althobaiti3
1Department of Surgery, Taif University, Taif, Saudi Arabia.
International journal of health sciences
|September 16, 2024
概括
像大豆奶这样的植物性雌激素补充剂 (PSs) 可能会降低乳腺癌 (BC) 风险. 然而, Echinacea,甘草根和绿茶补充剂可能会增加沙特妇女的BC风险.
科学领域:
- 营养与饮食学 营养与饮食学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 富含植物雌激素的补充剂 (PSs) 在全球范围内广泛用于潜在的乳腺癌 (BC) 风险降低.
- 在沙特阿拉伯,某些受欢迎的补充剂含有高水平的植物性雌激素.
- 了解这些补充剂对沙特人口中的BC风险的具体影响至关重要.
研究的目的:
- 调查常用植物雌激素补充剂 (PSs) 与沙特阿拉伯妇女乳腺癌 (BC) 风险之间的关联.
- 为了检查这种关联是如何根据更年期状态而变化的.
主要方法:
- 在2020年至2022年期间,在沙特阿拉伯五个省份进行了一项病例控制研究.
- 通过问卷从381个BC病例和449个无癌症对照组收集数据.
- 植物性雌激素补充剂的使用被评估为单独和多变量模型.
主要成果:
- 豆奶消费与BC风险显著降低有关.
- 切纳的使用与BC的风险增加有关.
- 甘草根和绿茶与分别在绝经前和绝经后妇女中增加BC风险有关.
结论:
- 豆异黄显示出降低BC风险的显著潜力,这表明它在修改后的预防策略中发挥了作用.
- ,甘草根和绿茶补充剂与BC风险增加有关,需要谨慎.
- 需要进一步的研究来阐明机制,并证实这些发现在不同的人群中.
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