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Updated: Jun 13, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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对新合成的三醇进行了抗菌和计算研究

Navneet Singh1, Vanika Mahant1, Ridhima Bhasin1

  • 1Department of Chemistry, School of Chemical Engineering and Physical Sciences, Lovely Professional University, Jalandhar-Delhi G.T. Road, Phagwara, Punjab 144411 India.

Indian journal of microbiology
|September 16, 2024
PubMed
概括

新的佐特醇衍生物显示出对细菌和真菌有前途的抗菌活性. 分子对接研究进一步支持它们的潜力,作为对抗抗菌素耐药性的新疗法.

关键词:
抗微生物药物 抗微生物药物佐特里亚 (佐特里亚) 是一种计算的计算 计算的计算在-Silico-Silico中使用.微波炉微波炉微波炉微波炉微波炉微波炉微波炉微波炉微波炉微波炉微波

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the...
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Bromination and chlorination of aromatic rings by electrophilic aromatic substitution reactions are easily achieved, but fluorination and iodination are difficult to achieve. Fluorine is so reactive that its reaction with benzene is difficult to control, resulting in poor yields of monofluoroaromatic products. To address this, Selectfluor reagent is used as a fluorine source in which a fluorine atom is bonded to a positively charged nitrogen.
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In the Sandmeyer reaction, for example, the diazonio group is replaced by a chloro, bromo,...
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Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
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Nitrous acid, a weak acid, is prepared in situ via the reaction of sodium nitrite with a strong acid under cold conditions. This nitrous acid prepared in situ reacts with primary arylamines to form arenediazonium salts. Such reactions are known as diazotization reactions. As shown in Figure 1, the formation of arenediazonium salts begins with the decomposition of nitrous acid in an acidic solution to give nitrosonium ions.
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