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Updated: Jun 13, 2025

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由MYO5B缺陷引起的细胞代谢途径和上皮细胞成熟的改变是LPAR5激活部分可逆的

Michael Momoh, Sudiksha Rathan-Kumar, Andreanna Burman

    bioRxiv : the preprint server for biology
    |September 16, 2024
    PubMed
    概括

    微型病毒包容性疾病 (MVID) 由于Myosin Vb (MYO5B) 损失而损害肠道功能. 用化合物-1准LPAR5通过改善肠道细胞功能和改善MVID模型中的症状,显示出治疗潜力.

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