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Updated: Jun 13, 2025

Screening Traditional Chinese Medicine Compounds for Inhibiting UCHL3 Activity Based on Molecular Docking and Deubiquitinating Enzyme Probe Technology
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Screening Traditional Chinese Medicine Compounds for Inhibiting UCHL3 Activity Based on Molecular Docking and Deubiquitinating Enzyme Probe Technology

Published on: November 22, 2024

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分子剂可以抑制二基酶活性和炎症信号传递

Francesca Chandler1, Poli Adi Narayana Reddy2, Smita Bhutda3

  • 1Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, UK.

bioRxiv : the preprint server for biology
|September 16, 2024
PubMed
概括

研究人员开发了新的BRISC分子剂 (BLUEs),通过稳定其二次体来选择性抑制BRISC复合物. 这种方法为治疗I型干扰素介导疾病提供了新的策略.

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