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Updated: Jun 13, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

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调节NLRP3与反意义寡核酸的拼接,以控制病理性炎症.

Roni Klein, Janset Onyuru, Estela M Viera

    bioRxiv : the preprint server for biology
    |September 16, 2024
    PubMed
    概括

    研究人员开发了拼接切换反感性寡核酸 (ASO) 以通过向NLRP3炎症酶来控制致病性炎症. 这种方法产生了非功能NLRP3蛋白质变体,在临床前模型中有效降低了炎症.

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