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Updated: Jun 13, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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SARS-CoV-2 Nsp15对抗cGAS-STING介导的抗病毒天生的免疫反应

Hsin-Ping Chiu1, Yao Yu Yeo2,3, Tsoi Ying Lai1

  • 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

bioRxiv : the preprint server for biology
|September 16, 2024
PubMed
概括

SARS-CoV-2 Nsp15 蛋白质通过向cGAS和STING,这些关键的先天免疫传感器来对抗宿主免疫系统. 破坏其内啡核糖酶活性会损害病毒复制并增强免疫反应.

关键词:
生物科学 / 微生物学在 Nsp15 中使用.这就是SARS-CoV-2病毒.cGAS-STING 的使用情况.具有天生的免疫力.

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