左心室尾关闭:在一个患有末期脏病高发病率的人群中,单个中心的经验
Luis A Areiza1, Juan F Rodriguez1, David Rodriguez1
1Interventional Cardiology Department, Hospital Universitario Mayor Méderi, Bogotá, D.C., COL.
Cureus
|September 16, 2024
概括
左心房尾关闭 (LAAC) 是安全有效的,以减少非膜心房的患者中风风险,包括那些在透析. 这项研究强调了它在西班牙裔人口中的可行性.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 左心房尾关闭 (LAAC) 为预防非膜心房动 (NVAF) 的中风提供了抗凝药的替代方案.
- 现有的LAAC数据往往低于西班牙裔人口,限制了对其在这个人口群体中的使用的理解.
- 这项研究解决了在西班牙裔队列中对LAAC数据的需求.
研究的目的:
- 描述接受LAAC的西班牙裔患者的人口,临床和程序特征.
- 评估LAAC在这个特定人群中的安全性和有效性.
- 评估在透析的末期病患者的结果.
主要方法:
- 在2017年6月至2022年7月接受皮穿式LAAC的成年患者的回顾性分析.
- 包括基线和程序数据.
- 在随访时评估严重出血,血栓塞栓事件和心血管死亡率;对透析患者的亚组分析.
主要成果:
- 包括33名西班牙裔患者;27名患者的平均随访时间为12.4个月.
- 平均年龄70岁,58%是女性;高的CHADS2 (3) 和HAS-BLED (4) 中位数表明高风险.
- 90天死亡率3.7%;每100个患者年率:心血管栓塞10.8,严重出血14.4.4. 透析患者的可比结果.
结论:
- 在高风险,多病症的西班牙裔人口中,LAAC是安全的,并且可用于降低血栓栓塞风险.
- 该程序在透析的末期病患者中证明了可行性.
- 这些发现支持LAAC作为在代表性不足的NVAF人群中作为一种替代性中风预防策略.
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