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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
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Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

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Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
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The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
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困难菌感染:一个更新.

Federica Salvati1, Francesca Catania1, Rita Murri1,2

  • 1Dipartimento di Sicurezza e Bioetica, Sezione di Malattie Infettive, Università Cattolica del Sacro Cuore, Rome, Italy.

Le infezioni in medicina
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PubMed
概括

克洛斯特里迪奥伊德困难感染 (CDI) 导致全球性腹. 新的治疗方法,如fidaxomicin和便微生物群移植 (FMT),改善了这一持续存在的医疗保健挑战的结果.

关键词:
克洛斯特里迪奥伊德斯困难菌在没有lotoxumabb的情况下.这就是fidaxomicin.

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科学领域:

  • 微生物学 微生物学
  • 传染性疾病 传染性疾病
  • 胃肠病学 胃肠病学

背景情况:

  • 困难菌 (C. difficile) 是全球腹的主要原因,由于高成本和长时间住院,造成了严重的医疗负担.
  • 像 ribotype 027 这样的高病毒性菌株导致了重大疫情爆发,而流行病学显示,社区获得的病例与医院获得的感染一起增加.
  • 困难菌的传播通过弹性子发生,医疗工作者和食物链的潜在作用,尽管食品传播尚未证实.

研究的目的:

  • 审查Clostridioides difficile感染 (CDI) 的流行病学,致病性,风险因素和不断变化的管理策略.
  • 突出CDI治疗的进展,包括新型治疗方法及其对患者结果和医疗保健系统的影响.

主要方法:

  • 对C. difficile流行病学,病原和临床管理的当前文献的综述.
  • 对既有和新兴疗法的治疗结果进行分析,包括抗生素,便微生物种移植和单克隆抗体.

主要成果:

  • 困难菌感染 (CDI) 呈现了一系列疾病,从轻微的腹到危及生命的结肠炎,死亡率和复发率很高.
  • 菲达克索米辛在减少CDI复发方面表现出优越的疗效,而便微生物群移植 (FMT) 对复发病例是有效的.
  • 贝兹洛托克苏马布在预防CDI复发方面充满希望,严重的病例可能需要手术.

结论:

  • 艰难菌感染 (CDI) 仍然是一个关键的临床挑战,需要持续的研究以改善患者的治疗结果.
  • 治疗方面的进步,包括菲达克索米辛,FMT和贝兹洛托马布,为CDI提供了改进的治疗选择,特别是对于复发性感染.
  • 为了减轻CDI对医疗保健系统的负担,需要继续研究预防和治疗策略.