使用对比增强超声波测量脑,和经过路时间测量和血液体积估计
Ken Monahan1, Deborah Kerrigan2, Cyndya Shibao3
1Division of Cardiovascular Medicine.
Ultrasound quarterly
|September 16, 2024
概括
与对比度增强的超声波可以测量大脑,和经过路时间和健康个体的血液体积. 这种技术对评估器官 perfusion 和血液流动动力学有很大的希望.
科学领域:
- 医疗成像医学成像
- 超声波技术 超声波技术 超声波技术
- 生理学 生理学 生理学
背景情况:
- 评估特定器官的血液流量和体积对于理解生理状态和疾病至关重要.
- 测量器官运输时间和血液体积的传统方法可能具有侵入性或缺乏精度.
- 与对比度增强的超声波 (CEUS) 提供了一种非侵入性的方法来可视化和量化血流动力学.
研究的目的:
- 用对比超声波测量大脑,和的传输时间和相关的血液体积.
- 评估这些测量的可复制性和可比性与参考值.
- 确定使用CEUS用于评估器官输液的可行性.
主要方法:
- 利用时间强度曲线从对比通过输入和输出血管 (大关节/关节,中腔/门口,动脉/静脉).
- 使用心率和传输时间计算器官血液体积相对于中风体积的计算.
- 估计的绝对器官血液体积使用输入血管特征和全身中风体积分数.
主要成果:
- 在大多数参与者中,大脑和脊柱区域的传输时间和血液体积都得到了成功.
- 测量结果显示,所有被评估的器官都具有可重现性.
- 脏过渡时间的获取被解剖学变异性所困扰,尽管获得了子集的数据.
- 获得的血液体积值通常与已确定的参考范围相比较.
结论:
- 与对比度增强的超声波是一种可行的方法,可以合理地获得大脑,脊柱和的传输时间和血液体积.
- 虽然脏测量存在挑战,但该技术显示出临床应用的潜力.
- 未来的研究应该专注于使用这种CEUS方法评估干预措施对区域血液体积的影响.
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