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Updated: Jun 13, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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神经提升器阵列:一个全基因组基因型平台,用于研究不同人群的神经疾病

Sara Bandres-Ciga1, Faraz Faghri1,2, Elisa Majounie3

  • 1Center for Alzheimer's and Related Dementias, National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.

Movement disorders : official journal of the Movement Disorder Society
|September 16, 2024
PubMed
概括

新的Illumina NeuroBooster Array (NBA) 通过包括多种祖先研究的多样化遗传内容来增强神经疾病研究. 这种阵列促进了全球人口的遗传发现和包容性.

关键词:
阿尔茨海默氏症和相关痴呆症中心全球帕金森病遗传学计划这是一个NeuroBooster阵列.多样性的多样性多样性的多样性基因查 基因查 基因查基因型定制是基因型定制.神经系统疾病 神经系统疾病

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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