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Updated: Jun 13, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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过度表达Igf2衍生的Mir483抑制Igf1的表达,并导致小鼠的发育生长限制和代谢功能障碍

Ionel Sandovici1, Denise S Fernandez-Twinn2, Niamh Campbell3

  • 1Medical Research Council Metabolic Diseases Unit, Institute of Metabolic Science-Metabolic Research Laboratories, University of Cambridge, Cambridge, UK; Department of Obstetrics and Gynaecology and National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.

Cell reports
|September 16, 2024
PubMed
概括

在Igf2基因中发现的MicroRNA 483 (Mir483) 作为增长抑制剂. 它的失调影响胎儿发育和新陈代谢,突出其在调节胰岛素类生长因子信号传递中的作用.

关键词:
CP: 发育生物学GH GH GH GH 的意思是什么?IGF1 IGF1 的一个例子.IGF2 IGF2是什么意思肥胖症是一种脂肪性.胎儿生长限制 限制胎儿生长基因组印记是基因组的印记.增长激素增长激素的使用方法类似胰岛素的增长因子1类似胰岛素的增长因子2代谢 代谢 代谢 代谢在 miR-483 的位置上.微RNAs 是一个微型RNA.在怀孕中期死亡率.

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