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美国明尼苏达州奥姆斯特德县甲状腺眼病的流行病学,2005-2020年

Kharisa N Rachmasari¹, Dana Hamadi¹, Prabin Thapa²

¹Division of Endocrinology, Diabetes, Metabolism and Nutrition, Mayo Clinic, Rochester, Minnesota, USA.

Thyroid : official journal of the American Thyroid Association

|September 16, 2024

概括

甲状腺眼病 (TED) 流行病学显示出稳定的发病率,女性患病率高于男性,特别是在50岁以后. 疾病进展与软组织参与和双眼视有关.

科学领域:

眼科医生眼科眼科
内分泌学在内分泌学.
流行病学流行病学

背景情况:

甲状腺眼部疾病 (TED) 是一种影响视轨道的自身免疫性疾病.
了解TED的流行病学对于资源分配和患者管理至关重要.

研究的目的:

描述在明尼苏达州奥姆斯特德县甲状腺眼病 (TED) 的流行病学.
计算发病率和流行率,并确定与疾病进展相关的因素.

主要方法:

新诊断TED患者的基于人口的队列研究 (2005-2020年).
纳入标准:年龄≥18岁.
发生率和流行率的计算;疾病特征和进展的描述.

主要成果:

发现了83起事件事件;90.4%是女性.
根据年龄调整的发病率:5例/100,000人/年 (女性:8.9;男性:1).
60-64岁和80-84岁的女性的峰值发病率;70-74岁的男性.
总体点患病率:65/100,000 (女性:114.5;男性:13.8). 总体点患病率:65/100,000 (女性:114.5;男性:13.8). 总体点患病率:65/100,000 (女性:114.5;男性:13.8). 总体点患病率:65/100,000 (65/100,000) 总体点患病率:65/100,000 (65/100,000) 总体点患病率:65/100,000 (65/100,000)
进展因素:软组织的参与 (HR 7.7) 和双眼视 (HR 2.5).

结论:

TED发病率保持稳定,但低于之前的估计.
女性在50岁以后表现出更早的峰值发病率和更大的疾病负担.
对TED的进一步研究,教育和管理策略是有必要的.

关键词:

格雷夫斯的眼科疾病.格雷夫斯的轨道病变症流行病学流行病学发生率的发生率.患病率的流行情况.甲状腺眼睛疾病甲状腺眼睛疾病

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