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Updated: Jun 13, 2025

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
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Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

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英格兰不同种族群体中ARB和ACEi的有效性和风险:使用英国临床实践研究数据链接Aurum相关数据的参考试验 (ONTARGET) 仿真分析

Paris J Baptiste1,2, Angel Y S Wong2, Anna Schultze2

  • 1Centre for Primary Care, Wolfson Institute of Population Health, Queen Mary University of London, United Kingdom.

PLoS medicine
|September 16, 2024
PubMed
概括

ангиотензин受体阻断剂 (ARBs) 和 ангиотензин转化酶抑制剂 (ACEi) 在黑人人群体中对高血压的有效性各不相同. 目前英国的指导方针可能会对黑人个人构成风险,原因是药物反应的种族差异.

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Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
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Angiotensin-converting enzyme (ACE), a vital component of the renin-angiotensin-aldosterone system, is abundant in lung endothelial cells. ACE converts the inactive decapeptide, angiotensin I, into the active octapeptide, angiotensin II. This potent vasoconstrictor narrows blood vessels, increasing resistance to blood flow and elevating blood pressure. Angiotensin II also stimulates aldosterone production, encouraging kidney cells to reabsorb more sodium and water from urine, thereby increasing...
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