2024OREF:

Christopher H Evans1, Steven C Ghivizzani, Paul D Robbins

  • 1From the Departments of Physical Medicine & Rehabilitation, Orthopedic Surgery and Molecular Medicine, Mayo Clinic, Rochester, NY (Evans), the Department of Orthopedics and Rehabilitation, University of Florida College of Medicine, Gainesville, FL (Ghivizzani), and the Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota School of Medicine, Minneapolis, MN (Robbins).

概括

基因疗法为骨关节炎治疗提供了一种新的方法,通过工程细胞在关节内局部产生治疗性蛋白质. 临床试验显示了对关节内基因转移的有希望的结果,这些基因转移的向是介素-1受体对抗剂.

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