副甲状腺切除术可以降低二次性副甲状腺功能障碍症患者的药物费用
Gabriel Mattucci Domingues Pereira1, Matheus Liao1, Sergio Samir Arap1
1Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
部分甲状腺切除术 (S-PTx) 和带自移植的全甲状腺切除术 (PTx-AG) 同样可以降低二次甲状腺功能障碍手术后的药物费用. 与女性相比,男性的长期门诊费用较高.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
背景情况:
- 二次性甲状腺功能障碍症 (SHPT) 的管理通常涉及甲状腺切除术.
- 部分甲状腺切除术 (S-PTx) 和完全甲状腺切除术与即时自移植 (PTx-AG) 是已确立的SHPT治疗方法.
- 需要对SHPT手术技术的长期经济影响进行分析.
研究的目的:
- 评估S-PTx与PTx-AG对术后药物费用的影响.
- 为了比较两种手术程序之间的药物使用和相关的医疗保健系统成本.
主要方法:
- 一项前性随机研究,比较重症SHPT患者的S-PTx和PTx-AG.
- 在多次术后间隔 (1-18个月) 分析处方药费用.
- 基于政府支付系统价值的成本估计.
主要成果:
- 手术在手术后12个月内降低了药物费用.
- 在S-PTx和PTx-AG组之间,每位患者的药物费用没有显著差异.
- 男性的药品总费用 (R$ 11,063.0) 比女性 (R$ 7,651.0) 高,男性的药品总费用比女性 (R$ 7,651.0) 高.
结论:
- 手术方法 (S-PTx与PTx-AG) 不影响手术后的药物费用.
- 在第一年,和醇是主要的药物;后来,sevelamer成为主要的成本驱动因素.
- 男性在副甲状腺切除术后的门诊随访费用较高.
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