慢性病中的心力衰竭死亡率:致命的交叉
Yong-Hao Yeo1, Boon-Jian San2, Xuan-Ci Mee3
1Department of Internal Medicine-Pediatrics, Corewell Health William Beaumont University Hospital, Royal Oak, MI.
The American journal of medicine
|September 16, 2024
概括
慢性病患者心力衰竭的死亡率从2011年到2020年显著增加. 针对性干预和政策变化对于这个弱势群体至关重要.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 对于患有并发性慢性病 (CKD) 的心力衰竭 (HF) 患者,现实世界死亡率数据有限,特别是在HF治疗的近期进展中.
- 了解这一群体的死亡率趋势对于制定有效的治疗策略和公共卫生干预措施至关重要.
研究的目的:
- 分析心力衰竭患者与伴随性慢性病的死亡率趋势.
- 确定患有CKD的患者心力衰竭死亡率的人口和区域差异.
主要方法:
- 利用CDC的WONDER数据库从2011年到2020年的死亡率数据.
- 包括25岁及以上的患者,这些患者主要死于心力衰竭和并发性慢性病.
- 计算了年龄调整的死亡率 (AAMR) 和使用Joinpoint回归来估计年度百分比变化 (APC) 的分析趋势.
主要成果:
- 总共记录了82,454例心力衰竭死亡与并发性CKD.
- 从2011年到2020年,患有CKD的HF的年龄调整死亡率 (AAMR) 增加了149.0%.
- 在男性,非洲裔美国人,中西部地区和农村地区观察到更高的AAMR. 大多数死亡发生在宿舍或养老院.
结论:
- 在CKD患者中观察到心力衰竭AAMR显著增加.
- 需要进一步的研究,以优化心脏保护疗法为这一群体.
- 在政策层面解决人口和区域差异至关重要.
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