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Updated: Jun 13, 2025

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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Published on: June 21, 2016

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PRDM3/16调节NKX2-1介导的膜上皮分化和功能所需的染色质可访问性

Hua He1,2, Sheila M Bell3, Ashley Kuenzi Davis3

  • 1Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China. Hua.he@scu.edu.cn.

Nature communications
|September 16, 2024
PubMed
概括

基因组甲基转移酶PRDM3和PRDM16对于肺部发育至关重要. 它们的缺失会导致呼吸衰竭,因为它会损害膜上皮细胞的分化和功能.

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A Method to Study de novo Formation of Chromatin Domains00:07

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