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Updated: Jun 13, 2025

Method for Measuring the Activity of Deubiquitinating Enzymes in Cell Lines and Tissue Samples
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Published on: May 10, 2015

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德尤比基提纳酶JOSD1可以缓解肝脏蛋白毒性

Saheli Chowdhury1, Abhishek Sen1,2, Debajyoti Das1,3

  • 1Division of Cell Biology and Physiology, CSIR-Indian Institute of Chemical Biology, Kolkata, India.

Cell death discovery
|September 16, 2024
PubMed
概括

研究人员确定了JOSD1,一种二基化酶 (DUB),可以保护肝细胞免受蛋白质毒性损伤. 通过稳定SOCS1,JOSD1增强了细胞活力并减少了细胞死亡,为肝脏疾病提供了潜在的治疗点.

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