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Updated: Jun 13, 2025

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer
09:24

3-D Cell Culture System for Studying Invasion and Evaluating Therapeutics in Bladder Cancer

Published on: September 13, 2018

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SPHK1通过PD-L2 / c-Src / FAK信号级联促进膀癌转移

Wei-Hsiang Kao1,2, Li-Zhu Liao2, Yu-An Chen2,3

  • 1Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan.

Cell death & disease
|September 16, 2024
PubMed
概括

斯芬哥辛激酶1型 (SPHK1) 通过激活PD-L2.2,驱动膀癌转移. 一种FDA批准的SPHK1抑制剂FTY720在临床前模型中有效抑制了癌症的扩散.

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