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与腰部疼痛相关的炎症性恶性瘤模仿脊髓炎
Fatih Albayrak1, Bünyamin Kısacık2, İbrahim Gündüz3
1Department of Internal Medicine, Division of Rheumatology, Gaziantep City Hospital, Şehitkamil, Gaziantep, Turkey. drfalbayrak@yahoo.com.
Clinical rheumatology
|September 16, 2024
概括
与恶性病相关的炎症性腰部疼痛与脊髓炎相比,呈现出更严重的临床画面和更高的生物标志物水平. 在差异诊断中早期考虑癌症对于及时干预至关重要.
科学领域:
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
- 诊断医学 诊断医学
背景情况:
- 炎症性腰部疼痛 (IBP) 是脊柱炎 (SpA) 的一个标志.
- 恶性瘤,包括血液和固体瘤,也可以通过副瘤效应或转移引起IBP.
- 区分恶性瘤诱导的IBP和SPA对于适当的患者管理至关重要.
研究的目的:
- 描述因恶性瘤而出现IBP的患者的人口和临床特征.
- 将这些特征与被诊断为轴性SPA的患者的特征进行比较.
主要方法:
- 10年来对34名患有恶性瘤相关IBP的患者进行了回顾性分析.
- 纳入36名轴性SPA患者作为对照组,根据年龄和性别进行匹配.
- 临床表现,诊断间隔和实验室标记的比较.
主要成果:
- 在恶性瘤相关的IBP中,血液和固体瘤的比例相等 (18/16).
- 与恶性瘤相关的IBP患者的症状-诊断间隔较短.
- 与对照组相比,恶性瘤组中观察到显著增加的红细胞沉积率 (ESR),C反应蛋白 (CRP) 和乳酸脱酶 (LDH) 水平.
结论:
- 与恶性性IBP相关的IBP表现出更严重的临床特征,急性相反应剂和LDH的升高.
- 在IBP的差异诊断中应考虑恶性病变,特别是当怀疑SPA时.
- 需要对更大的队列进行进一步研究,以验证这些发现并确定特定的致病性恶性瘤.
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