在急性缺血性中风患者中积极使用呼吸道治疗的现实世界挑战和障碍
Maeve Pascoe1, Madeleine M Grigg-Damberger2, Harneet Walia3
1Department of Neurology, Sleep Disorders Center, Cleveland Clinic Neurological Institute, 9500 Euclid Avenue, S73, Cleveland, OH, 44195, USA.
Sleep & breathing = Schlaf & Atmung
|September 16, 2024
概括
在急性缺血性中风 (AIS) 患者中诊断和治疗阻塞性睡眠呼吸暂停 (OSA) 是具有挑战性的. 这项研究发现,在这个人群中实施便携式监测和正气道压力疗法存在现实难题.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 心血管研究研究心血管研究
背景情况:
- 未经治疗的阻塞性睡眠呼吸暂停 (OSA) 与急性缺血性中风 (AIS) 患者的治疗结果更差有关.
- 在AIS患者中诊断和治疗OSA存在重大挑战.
- 在这个脆弱人群中有效管理OSA对于改善患者发病率和死亡率至关重要.
研究的目的:
- 评估使用便携式监测 (PM) 在住院AIS患者中诊断OSA的可行性.
- 为了评估正气道压力 (PAP) 治疗治疗OSA在这个队列中的有效性.
- 了解在住院中风环境中与OSA诊断和治疗相关的实际挑战.
主要方法:
- 招募AIS住院患者进行便携式监测 (PM) 以诊断OSA.
- 为符合条件的参与者提供自动定位的正气道压力 (APAP) 治疗 (呼吸事件指数≥10).
- 通过问卷和总结的临床结果收集了易用性数据.
主要成果:
- 该研究因外部因素而面临过早终止,限制了样本大小.
- 便携式监控 (PM) 在21名参与者中成功尝试了18名,并被评为易于使用.
- 只有27.8%的符合条件的患者长期使用APAP治疗,观察到显著的坚持和故障排除问题.
结论:
- 在AIS患者中对OSA评估和治疗的现实实施具有挑战性.
- 治疗PM和APAP的可行性受到患者坚持和后勤障碍的限制.
- 需要进一步的研究,以制定及时和实用的查和治疗策略,以对AIS的OSA进行治疗.
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