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Updated: Jun 13, 2025

Methodology for Accurate Detection of Mitochondrial DNA Methylation
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基本方程将甲基化动态与哺乳动物的最大寿命联系起来

Steve Horvath1,2,3, Joshua Zhang4, Amin Haghani4,5

  • 1Department of Human Genetics, University of California, Los Angeles, CA, USA. shorvath@altoslabs.com.

Nature communications
|September 16, 2024
PubMed
概括

双价促体区域的甲基化变化率与哺乳动物的最大寿命相反相关. 这种衰老生物标志物关系是特定于染色质背景的,而不是一般的甲基化水平.

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