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Updated: Jun 13, 2025

Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
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Published on: December 21, 2021

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对SIRT1的动力学和必要性对于母性-胚胎过渡的SIRT1的动力学和必要性

Jan Nevoral1,2, David Drutovic3, Michaela Vaskovicova3

  • 1Faculty of Medicine in Pilsen, Biomedical Center, Charles University, Alej Svobody 76, 323 00, Pilsen, Czech Republic. jan.nevoral@lfp.cuni.cz.

Scientific reports
|September 16, 2024
PubMed
概括

胚胎Sirtuin-1 (SIRT1) 对于胚胎基因组激活 (EGA) 周围的早期发育至关重要. 这种依赖NAD+的基因素脱乙酶独立于转录起作用,突出显示了它在孕产妇-胚胎过渡 (MZT) 中的非表观遗传作用.

关键词:
胚胎 胚胎是一个胚胎.胚胎基因组激活活动表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.希斯脱乙酶的使用情况卵细胞,雄细胞

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