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Updated: Jun 13, 2025

Confocal Imaging of Double-Stranded RNA and Pattern Recognition Receptors in Negative-Sense RNA Virus Infection
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Published on: January 26, 2019

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RNF144B通过向MDA5进行自性降解来负面调节抗病毒免疫力

Guoxiu Li1,2,3, Jing Zhang4,5, Zhixun Zhao1,3

  • 1State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730000, China.

EMBO reports
|September 16, 2024
PubMed
概括

RNF144B负面调节了对病毒的天生的免疫反应. 它针对MDA5进行降解,增强感染EMCV的小鼠的存活率.

关键词:
E3 结合酶 结合酶具有天生的免疫力.MDA5 MDA5 MDA5 是一个简单的数字.在 RNF144B 中.这是一种I型干扰素.

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