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哺乳,乳房检查密度和乳腺癌风险之间的关联:一篇综述
Dong-Man Ye1, Xiaoru Bai1, Shu Xu1
1Department of Medical Imaging, Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital & Institute, No.44 Xiaoheyan Road, Dadong District, Shenyang, 110042, China.
International breastfeeding journal
|September 16, 2024
概括
哺乳通过减少乳房检查密度,对乳腺癌产生保护作用. 持续母乳养后的逐渐卷入导致乳腺组织的有利变化,与突然卷入不同.
科学领域:
- 生殖健康 生殖健康
- 在瘤学瘤学.
- 分子生物学分子生物学
背景情况:
- 乳腺扫描密度是已知的乳腺癌风险因素.
- 母乳养与乳腺癌风险降低有关,特别是在攻击性亚型.
- 关于乳腺扫描密度,母乳养和乳腺癌的相互作用的研究是有限的.
研究的目的:
- 审查母乳养对乳腺扫描密度的影响.
- 探索母乳养在降低乳腺癌风险中的作用.
- 综合当前的流行病学和分子发现.
主要方法:
- 流行病学和分子生物学研究的文献综述.
- 在怀孕,哺乳期和发育过程中对乳腺组织变化的分析.
- 检查受母乳养影响的分子机制.
主要成果:
- 母乳养会影响乳腺微环境和乳房密度.
- 突发的内置 (由于早期停止) 会导致更密集的肌层,改变的原蛋白,炎症和激素受体表达的增加.
- 从持续的母乳养中逐渐的内置促进了缓慢的组织重塑.
- 哺乳可以通过益生菌素和母乳成分调节DNA甲基化.
结论:
- 哺乳显然与乳腺癌风险的降低有关,因为乳腺扫描密度的变化.
- 需要对不同族群和潜在的分子机制进行进一步的研究.
- 了解这些关联可以为乳腺癌预防和治疗策略提供信息.
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