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Updated: Jul 27, 2026

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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对胎盘组织处理的技术考虑以及随后对全基因组DNA甲基化分析的影响

Kristen M Kocher1,2, Julius Ngwa1, Kushal J Kapse1

  • 1Developing Brain Institute, Center for Prenatal, Neonatal and Maternal Health Research, Children's Research Institute, Children's National Hospital, Washington, DC, USA.

Clinical epigenetics
|September 16, 2024
PubMed
概括

产后处理影响胎盘DNA甲基化分析. perfluorocarbon浸泡是合适的,但甲胺固定损害了表观遗传学研究的数据可靠性.

关键词:
通过DNA甲基化.基因表观衰老 基因表观衰老 基因表观衰老在FFPE的FFPE.胎盘 胎盘 胎盘 胎盘

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相关概念视频

Sanger Sequencing01:57

Sanger Sequencing

DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...