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Updated: Jun 13, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
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Published on: August 15, 2017

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ERK1/2通过调节DRP1-介导的线粒体动态调节来调节发作

Ting Chen1, Juan Yang1, Yongsu Zheng1

  • 1Department of Neurology, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, P. R. China.

Synapse (New York, N.Y.)
|September 17, 2024
PubMed
概括

发作后细胞外信号调节激酶 (ERK1/2) 的过度激活导致线粒体功能障碍. 抑制ERK1/2信号通过降低DRP1酸化的调节来降低发作易感性,从而减轻病原体.

关键词:
与胺相关的蛋白质1是一种.细胞外调节蛋白激酶 1/2 细胞外调节蛋白激酶 1/2线粒体分裂的线粒体裂变

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