在开饮食开始时,肝功能测试的急性变化
Akshat Katyayan1, Anuranjita Nayak1, Gloria Diaz-Medina1
1Department of Pediatric Neurology and Developmental Neuroscience, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Journal of child neurology
|September 17, 2024
概括
用于的性饮食可以导致急性肝功能变化. 调整药物或添加胆往往使患者能够成功地继续饮食.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 饮食疗法是一种饮食疗法.
背景情况:
- 性饮食是对抗药性的公认治疗方法.
- 虽然通常是安全的,但潜在的副作用包括胃肠道问题,很少出现长期肝毒性.
- 有限证据表明,饮食在急性肝损伤中的作用有限.
研究的目的:
- 为了调查急性肝功能测试异常的发生和模式,在开始食期间测试异常.
- 评估基因饮食对医疗耐药性患者肝功能的影响.
主要方法:
- 从2019年6月到2022年6月,对25名患者进行了回顾性分析,这些患者从2019年6月到2022年6月接受了住院基因素饮食启动.
- 对肝细胞和胆固醇模式的肝功能测试 (LFTs) 的监测.
- 评估干预措施,如停止饮食,调整药物或补充胆.
主要成果:
- 25名患者中有6名 (24%) 在开始饮食期间表现出急性无症状的LFT变化.
- 这些变化出现在肝细胞和胆固醇模式中.
- 两名患者停止了饮食,而三名患者继续服用药物调整或胆;所有患者都显示短期LFT正常化. 一名患者经历了先前升高的LFTs的正常化.
结论:
- 开性饮食可以导致急性无症状的肝功能检测异常,包括肝细胞和胆固醇模式.
- 这些变化可以独立于同时服用肝毒药物而发生.
- 性饮食通常可以在适当的管理下安全地继续,例如药物修改或胆补充剂.
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