doxorubicin 和 trabectedin 治疗复发性乳腺肌肉瘤 - 一个案例报告
Gabriel Levin1, Lucy Gilbert2, Shuk On Annie Leung2
1Division of Gynecologic Oncology, McGill University, Montreal, Quebec, Canada.
Gynecologic oncology reports
|September 17, 2024
概括
doxorubicin 加上 trabectedin 显示为对复发性子宫乳腺肌肉瘤 (LMS) 的二线治疗,这是一个罕见而具有攻击性的癌症. 这种组合化疗导致了一种显著的部分反应,并延长了晚期LMS患者的无进展生存期.
科学领域:
- 妇科瘤学 妇科瘤学
- 医学瘤学 医学瘤学
- 药理学 药理学是指药理学的学科.
背景情况:
- 子宫乳腺肌肉瘤 (LMS) 是一种罕见的,具有攻击性的恶性瘤,治疗选择有限.
- 目前的第一线疗法,如多克索鲁比辛或格姆奇塔宾/多克塔克塞尔,提供适度的反应率.
- 根据LMS-04研究,多克索鲁比辛和特拉贝克丁的组合是首选的第一线选择.
更多相关视频
04:04Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
10.4K
13:41Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
Published on: January 13, 2023
2.3K
相关概念视频
02:56Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
02:56Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...