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对抗者与血管压素V1b受体结合的结构基础由分子动力学模拟揭示

Magdalena J Ślusarz1

  • 1Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland.

Biopolymers
|September 17, 2024
PubMed
概括

尼利瓦普坦是一种V1bR抗剂,通过抑制下丘脑-垂体-上腺轴,在与压力相关的疾病中显示出有希望的治疗潜力. 分子动力学模拟揭示了它在V1b受体内的结合机制和选择性.

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