超直流刺激对高血压:一个系统的审查和元分析
Edson Silva-Filho1,2, Quênia Gramile Silva Meira2, Ayrlla Da Costa Rodrigues2
1Graduate Program in Rehabilitation Science, Federal University of Rio Grande do Norte, Rio Grande do Norte, Brazil.
Acta cardiologica
|September 17, 2024
概括
经直流刺激 (tDCS) 可能在一次治疗后改善高血压的血液动力学和自主性参数. 在主要运动皮层上进行的阳极刺激似乎对高血压个体调节血压最有效.
科学领域:
- 神经科学是一个神经科学.
- 心血管医学 心血管医学
- 生物医学工程 生物医学工程
背景情况:
- 高血压是一个普遍存在的全球健康问题,具有显著的发病率和死亡率,尽管存在治疗方法.
- 跨直流刺激 (tDCS) 提供了一种便携式的,非侵入性的方法来调节中枢神经系统,并可能控制心血管功能.
- 目前治疗高血压的治疗策略存在局限性,需要探索新的干预措施.
研究的目的:
- 系统地审查和评估tDCS对高血压患者血液动力学和自主性参数的影响.
- 综合从临床试验中调查tDCS作为隔离或辅助治疗高血压管理的结论.
- 评估tDCS在高血压人群中调节心血管和自主标志物的疗效和安全性.
主要方法:
- 进行了临床试验的系统审查,搜索主要数据库,查找在高血压参与者中使用tDCS的研究.
- 包括的研究集中在旨在调节血液动力学和自主性参数的tDCS干预措施上.
- 进行了元分析以计算效果大小,并在符合条件的研究中评估了偏差风险.
主要成果:
- 四项研究符合纳入标准,其中一些表明单次tDCS会话后血液动力学和自主性参数得到改善.
- 分析显示,缩和腹缩血压下降的趋势,以及心率变化 (RMSSD) 的改善,尽管对所有措施来说都不具有统计学意义.
- 经过十次tDCS会话后没有观察到任何显著差异,所有纳入的研究都表明偏差风险低.
结论:
- 单次,孤立的tDCS可以有效调节高血压患者的血液动力学和自主性参数.
- 针对主要运动皮质的阳刺激显示出作为诱导有益心血管反应的最佳策略的承诺.
- 需要进一步的研究来优化tDCS协议,以持续控制高血压的持续血压管理.
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