对患有心房动的成年人进行基于运动的心脏康复治疗
Benjamin JR Buckley1,2, Linda Long3, Signe S Risom4
1Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital, Liverpool, UK.
The Cochrane database of systematic reviews
|September 17, 2024
概括
基于运动的心脏康复 (ExCR) 可能会减少心房的复发和症状负担. 然而,它对死亡率和严重不良事件的影响仍然不确定,需要进一步进行高质量的研究.
科学领域:
- 心脏病学和心脏康复中心
- 节律失常的管理管理
- 临床试验分析
背景情况:
- 心房动 (AF) 是最常见的心律失常,增加中风,心力衰竭和降低生活质量的风险.
- 基于运动的心脏康复 (ExCR) 正在探索其在管理AF方面的潜在益处.
- 全球AF发病率日益增加,凸显出需要有效的管理策略.
研究的目的:
- 评估基于运动的心脏康复 (ExCR) 的益处和危害,与非运动对照对象相比,在患有AF的人群中.
- 对AF患者的ExCR进行随机临床试验 (RCT) 的综合证据.
主要方法:
- 系统地搜索多个电子数据库和临床试验注册表.
- 包括20个RCT,涉及2039名AF参与者,随访期从8周到5年.
- 使用随机效应模型的元分析和使用GRADE方法评估证据确定性.
主要成果:
- ExCR可能会减少AF复发 (中等确定性),AF症状严重程度和负担 (低至中等确定性),以及AF情节持续时间 (中等确定性).
- ExCR可能会改善与健康相关的生活质量 (HRQoL) (中等确定性) 的心理组成部分.
- 证据表明,ExCR和对照组之间死亡率 (低确定性) 和对严重不良事件 (低确定性) 的不确定的影响几乎没有差异.
结论:
- 基于运动的心脏康复 (ExCR) 在改善AF特异性结果,如复发和症状以及心理HRQoL方面表现有前途.
- 由于数据有限和随访时间短,ExCR对AF患者的死亡率和严重不良事件的影响目前尚不确定.
- 需要高质量的RCT来进一步评估ExCR对患者相关结果的有效性,并探索AF亚型和临床环境的影响.
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