在突尼斯新生儿重症监护病房的非常早产婴儿中,支气管肺形的患病率和危险因素
Mouadh Benali1, Nourzed Ben Hamida1, Salsabil Jaouhari1
1University of Tunis ElManar, Faculty of Medicine of Tunis, 1068, Charles Nicolle University Hospital, Service of Neonatology, 1006, Tunis, Tunisia.
La Tunisie medicale
|September 17, 2024
概括
支气管肺功能障碍 (BPD) 影响超过三分之一的非常早产婴儿,母亲的高血压障碍,胸膜炎,IUGR,早孕和机械通风是关键的危险因素. 这种情况显著增加了早产婴儿的死亡风险.
科学领域:
- 新生儿科学 新生儿科学
- 儿科肺病学 儿科肺病学
- 围产儿医学 围产儿医学
背景情况:
- 支气管肺功能障碍症 (BPD) 是早产婴儿的主要慢性呼吸道疾病.
- 其日益增长的患病率,死亡率和社会经济影响凸显了严重的公共卫生问题.
- 了解BPD的风险因素对于改善脆弱新生儿的治疗结果至关重要.
研究的目的:
- 为了确定非常早产婴儿中BPD的流行率.
- 为了确定与BPD发展相关的独立风险因素.
- 分析BPD对该人口死亡率的影响.
主要方法:
- 对早产婴儿 (妊娠26-31周) 存活超过28天的回顾性,描述性和分析性研究.
- 数据是在五年 (2017-2021) 期间收集的.
- BPD定义为至少28天需要补充氧气;用于确定风险因素的多变量分析.
主要成果:
- 经月经后28天的BPD患病率为37.7%,经月经后36周的患病率为36.7%.
- 独立的危险因素包括孕产妇高血压障碍,肌炎,子宫内生长限制 (IUGR),妊娠年龄<30周和机械通风 (MV).
- 与没有BPD的婴儿相比,BPD的婴儿 (10.3%) 的死亡率明显高 (0.7%).
结论:
- 在非常早产的婴儿中,BPD的患病率很高.
- 孕产妇高血压障碍,IUGR,膜炎,MV和早期妊娠年龄 (<30周) 是BPD的重要独立风险因素.
- BPD与非常早产婴儿的死亡风险大幅增加有关.
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