在单冠状同位症中变形性脑的发生率和形态学
Hyok Jun Kwon1, Roland Deek, Lachlan D M Farmer
1Cleft and Craniofacial South Australia, Women's and Children's Hospital, North Adelaide, Adelaide, Australia.
The Journal of craniofacial surgery
|September 17, 2024
概括
单冠状结合症和变形性脑性脑常常同时存在. 变形性脑症不会影响单角性阴位症患者的头骨或轨道形状.
科学领域:
- 面外科手术 面外科手术
- 儿科神经外科 儿科神经外科
- 发育生物学是发展生物学.
背景情况:
- 单冠状结合症和变形头症 (DP) 是影响婴儿头部形状的不同疾病.
- 患有独角兽同位症和DP的患者的同时发生和特异性仍未得到充分研究.
- 了解这种重叠对于准确的诊断和管理至关重要.
研究的目的:
- 调查联合独角兽同位症和DP的发生率和表型表现.
- 分析DP对独角兽同位症患者内和轨道形态学的影响.
- 在这个患者队列中描述ipsilateral和contralateral DP之间的差异.
主要方法:
- 对被诊断患有独角兽同位症的患者的回顾性审查.
- 分析3D计算机断层扫描 (3DCT) 扫描以确定DP的存在和类型.
- 在所有被纳入的患者中评估内和轨道形态.
主要成果:
- 有一个显著的比例 (38.4%) 的单角性同位症患者也出现了DP.
- 阴性边缘DP的频率低于反边缘DP.
- 患有ipsilateral DP的患者表现出由于额头不对称性减少而延迟表现的倾向.
- 在独角兽同位症的背景下,变形性脑并没有显著改变内或轨道形态.
结论:
- 在儿科患者中,单冠结合症和DP经常一起发生.
- 无论侧面状况如何,DP的存在都不会影响独角兽同位症中底层的头骨或轨道形态.
- 临床表现,特别是额头不对称,可能会根据DP横向性而有所不同.
相关概念视频
Sutures of the Skull
6.4K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.4K
Cranial Bones: Superior and Posterior View
2.0K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
2.0K
Neurulation
41.7K
Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
41.7K
Deformations in a Symmetric Member in Bending
163
When analyzing the deformation of a symmetric prismatic member subjected to bending by equal and opposite couples, it becomes clear that as the member bends, the originally straight lines on its wider faces curve into circular arcs, with a constant radius centered at a point known as Point C. This phenomenon helps to understand the stress and strain distribution within the member more clearly.
When the member is segmented into tiny cubic elements, it is observed that the primary stress...
When the member is segmented into tiny cubic elements, it is observed that the primary stress...
163
Deformations in a Transverse Cross Section
180
When a material is subjected to uniaxial stress, it elongates or contracts in the direction of the applied force, and also undergoes changes in the perpendicular directions. This behavior is crucial for understanding how materials behave under stress and is governed by mechanical properties such as Poisson's ratio v, which measures the ratio of transverse strain to axial strain.
As the material stretches, it expands or contracts in orthogonal directions to the load. This phenomenon varies...
As the material stretches, it expands or contracts in orthogonal directions to the load. This phenomenon varies...
180
Plastic Deformations
84
It is essential to understand how structural members behave under plastic deformation when the bending stress exceeds the material's yield strength. This state of deformation permanently alters the shape of the member, in contrast to the linear elastic behavior observed before yielding. The strain at any point in the member is expressed in terms of maximum strain. Notably, the neutral axis, which coincides with the centroid during elastic bending, shifts away from the centroid under plastic...
84


