相关实验视频

Updated: Jun 12, 2025

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function
09:20

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

Published on: May 4, 2021

3.6K

微RNA作为肥胖的表观遗传调节剂

Ayse Basak Engin1, Atilla Engin2,3

  • 1Faculty of Pharmacy, Department of Toxicology, Gazi University, Hipodrom, Ankara, Turkey. abengin@gmail.com.

Advances in experimental medicine and biology
|September 17, 2024
PubMed
概括

微RNAs (miRNAs) 通过控制脂肪生成和细胞间通信,在调节肥胖方面发挥着至关重要的作用. 失调的miRNA具有作为肥胖及其相关并发症的生物标志物和治疗点的潜力.

关键词:
脂肪细胞衍生微片 (ADM) 是一种微片.增脂生殖是一种增脂的过程.亚迪波尼克丁氨酸是什么赛提丁-赛提丁-氨酸-氨酸-氨酸-氨酸 (CCAAT) /增强剂结合蛋白 (C/EBP)脂肪酸结合蛋白4 (FABP4) 是一种脂肪酸结合蛋白.叉头盒子蛋白质O1 (FoxO1) 是一种胰岛素耐药性 胰岛素耐药性是一种介素1 (IL-1) 受体关联激酶-1 (IRAK-1) 的作用.勒普丁是一种激素.脂质的滴滴,就是脂质滴滴.脂肪毒性 脂肪毒性微型核糖核酸-143 (miR-143) 是一个微型核糖核酸.微核糖核酸-103 (miR-103) 是一种微核糖核酸.微核糖核酸-148a (miR-148a) 是一种微核糖核酸.微核糖核酸-155 (miR-155) 是一种微核糖核酸.微核糖核酸-221 (miR-221) 是一种微核糖核酸.微核糖核酸-223 (miR-223) 是一种微核糖核酸.微核糖核酸-33 (miR-33) 是一种微核酸.微核糖核酸-34 (miR-34) 的使用微核糖核酸 (miRNA) 是一种微核糖核酸.肥胖问题 肥胖问题氧化低密度脂蛋白 (Ox-LDL) 是一种氧化低密度脂蛋白.过氧体增殖器激活的受体-玛 (PPAR-γ)无声信息调节器1 (SIRT1) 是一个无声信息控制器.固醇调节元素结合蛋白 (SREBP) 是一种收费类受体4 (TLR4) 是一个收费类受体.甘油三化物是一种三糖化物.瘤亡因子受体 (TNFR) 相关因子6 (TRAF6)瘤亡因子-阿尔法 (TNF-α)减肥的方法 减肥的方法 减肥的方法

更多相关视频

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies14:56

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

4.4K
CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis10:40

CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis

Published on: April 25, 2022

2.3K

相关概念视频

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
21.2K
Epigenetic Regulation01:46

Epigenetic Regulation

Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
30.9K
Regulation of Food Intake01:30

Regulation of Food Intake

Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
204
Master Transcription Regulators02:23

Master Transcription Regulators

Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
6.9K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.1K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
8.5K