Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Proteomics01:33

Proteomics

7.2K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Freeze-dried kit formulation and physicochemical assessment of a daratumumab-based radiopharmaceutical.

Acta pharmaceutica (Zagreb, Croatia)·2026
Same author

<i>ATM</i> Variants and Breast Cancer Risk in North Macedonia: Focus on the Regionally Enriched <i>p.(Leu2492Arg)</i> Variant.

Balkan medical journal·2026
Same author

S-Doped Carbon Dot Treatment Alters RNA Processing, Translation, and Protein Degradation Pathways in HeLa Cells.

Current issues in molecular biology·2026
Same author

Genotype-Phenotype Correlation in Tuberous Sclerosis Complex: Insights from North Macedonia

Balkan medical journal·2026
Same author

Toward clinical application of whole-exome sequencing in the diagnosis of men with severely impaired spermatogenesis.

Fertility and sterility·2025
Same author

The role of DNA mismatch repair mutS/mutL homolog genes in spermatogenesis and male infertility: a systematic review and cohort study.

Reproductive biology and endocrinology : RB&E·2025

相关实验视频

Updated: Jun 12, 2025

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.3K

解读复发性妊娠损失:比较蛋白质组学研究的见解

Katarina Davalieva1, Damjan Kocarev1, Dijana Plaseska-Karanfilska1

  • 1Research Centre for Genetic Engineering and Biotechnology "Georgi D Efremov", Macedonian Academy of Sciences and Arts, Krste Misirkov 2, 1000 Skopje, North Macedonia.

Biology of reproduction
|September 17, 2024
PubMed
概括

复发性流产 (RPL) 影响2%的女性,超过一半的病例原因不明. 蛋白质组分析提供了对RPL病原体和潜在生物标志物的洞察.

科学领域:

  • 生殖生物学 生殖生物学
  • 蛋白质组学是指蛋白质组学.
  • 生物标志物发现发现

背景情况:

  • 重复流产 (RPL) 影响高达2%的女性,导致严重的情感和社会痛苦.
  • 在超过50%的受影响个体中,RPL的根本原因仍未确定.
  • 对比蛋白质组分析为阐明RPL复杂病变发生提供了一个有希望的途径.

研究的目的:

  • 批判性地评价已发表的比较性蛋白质组学研究,对来自RPL妇女的人体样本进行了比较.
  • 巩固对分析材料,蛋白质组学平台和确定候选生物标记物的发现.
  • 概述与RPL相关的改变的生物途径和过程.

主要方法:

  • 在PubMed和谷歌学者数据库的系统文献搜索.
  • 包括使用RPL妇女人体样本进行的比较蛋白质学研究.
  • 对高通量蛋白质组数据的生物信息学分析.

主要成果:

  • 分析的各种人体样本类型的详细概述 (例如,胆管,决定体,胎盘,子宫内膜,母体血液).
  • 确定和讨论与RPL相关的顶级候选生物标志物和改变的途径.
  • 介绍涉及RPL病变的常见生物过程和途径.
关键词:
生物标志物生物标志物蛋白质组学 蛋白质组学经常发生的怀孕流产.这是自发流产.

更多相关视频

Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells
07:46

Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells

Published on: October 13, 2023

1.2K
Quantitative Analysis of Chromatin Proteomes in Disease
08:11

Quantitative Analysis of Chromatin Proteomes in Disease

Published on: December 28, 2012

13.1K

相关实验视频

Last Updated: Jun 12, 2025

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

3.3K
Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells
07:46

Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells

Published on: October 13, 2023

1.2K
Quantitative Analysis of Chromatin Proteomes in Disease
08:11

Quantitative Analysis of Chromatin Proteomes in Disease

Published on: December 28, 2012

13.1K

结论:

  • 对比蛋白质组学已经确定了候选生物标志物和RPL中的改变途径.
  • 需要进一步的研究来将这些发现转化为诊断和治疗策略.
  • 未来的方向集中在开发RPL的新和有效的治疗方法.