膝关节结核病:一个被忽视的临床实体
Ran Cui1, Qing Huang1, Sheng-Ming Dai1
1Department of Rheumatology and Immunology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Journal of infection in developing countries
|September 17, 2024
概括
结核性膝关节关节炎可以潜伏地出现,模仿其他疾病,如PVNS. 早期考虑Mycobacterium结核菌感染对于准确诊断和治疗慢性膝关节关节炎至关重要.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 放射学 放射学是指放射学
背景情况:
- 肺外结核通常会影响淋巴结,肺,骨,关节,泌尿器官和脑膜.
- 结核性关节炎由于异常表现和非特异性成像,造成了诊断挑战.
- 早期诊断往往由于阴险的临床表现而延迟.
研究的目的:
- 为了突出结核膝关节关节炎的诊断挑战.
- 强调在慢性膝关节关节炎的差异中考虑Mycobacterium结核病 (MTB) 的重要性.
主要方法:
- 一份病例报告显示,一名59岁的男性患有慢性左膝胀,最初被误诊为PVNS.
- 使用了X射线,MRI,CT扫描和干扰素-γ释放试验 (IGRA).
- 通过聚合酶链反应 (PCR) 检测MTBDNA在突液中的诊断证实了诊断,并呈阳性IGRA.
主要成果:
- 患者出现了持续的膝盖胀,尽管先前的全膝关节整形术 (TKA).
- 放射学和实验室评估表明结核性膝关节关节炎.
- 通过PCR检测MTBDNA和阳性IGRA证实结核性关节炎.
结论:
- 结核性膝关节关节炎需要高的怀疑指数,因为不典型的表现.
- 慢性单侧膝关节关节炎的差异诊断必须包括MTB感染.
- 早期和准确的诊断至关重要,特别是当条件模仿PVNS或其他关节病理时.
相关概念视频
Pulmonary Tuberculosis III
312
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
312
Pulmonary Tuberculosis IV
134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis II
213
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
213
Pulmonary Tuberculosis V
172
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
172
Pulmonary Tuberculosis I
224
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
224
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture
168
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
168


