单独生活的肺癌老年人的功能,认知和生活质量:一项前性队列研究
Surbhi Singhal1, Louise C Walter2, Alexander K Smith2
1Division of Hematology/Oncology, Department of Medicine, University of California, Davis, Sacramento, CA, USA.
Journal of geriatric oncology
|September 17, 2024
概括
单独生活的非小细胞肺癌 (NSCLC) 的老年人在治疗期间与与他人生活的人相比,保持了类似的功能,认知和生活质量 (QOL). 对这个人群来说,个性化支持性护理是可行的.
科学领域:
- 老年瘤学 老年瘤学
- 临床瘤学临床瘤学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 孤独生活与没有癌症的老年人健康状况不佳有关.
- 关于在全身治疗期间独自生活的非小细胞肺癌 (NSCLC) 的老年人功能,认知和生活质量 (QOL) 的数据有限.
研究的目的:
- 研究孤独生活对高级非小细胞肺癌 (NSCLC) 接受全身治疗的老年人功能,认知和生活质量的影响.
主要方法:
- 149名老年人 (≥65岁) 患有晚期NSCLC,开始新的全身疗法被纳入.
- 包括日常生活工具活动 (IADL),认知功能和QOL在内的老年人评估在治疗前和6个月后的随访点进行.
- 使用多项逻辑回归来比较单独生活的患者与其他患者之间的结果.
主要成果:
- 治疗前IADL,认知和QOL的得分在各组之间是相似的.
- 在NSCLC治疗期间,大约一半的单独生活的患者经历了功能,认知和QOL的下降,其轨迹与与与他人一起生活的人相似.
- 未经调整的分析显示,单独生活的人的功能衰退与恢复的可能性更高,但经过调整后,这并不显著.
结论:
- 与那些与他人生活在一起的人相比,独自生活的晚期NSCLC的老年人在全身治疗期间保持了类似的功能,认知和QOL.
- 对于许多独自生活的老年人来说,先进的NSCLC的全身治疗是可行的,前提是提供个性化的支持性护理.
相关概念视频
02:20Longitudinal Research
11.9K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.9K
01:30Cognitive Development During Adulthood
66
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
66
01:20Lifestyle Factors and Health
38
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
38
01:26COPD: Management Using Bronchodilators and Corticosteroids
186
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
186
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
01:26Longitudinal Studies
142
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
142