不确定性概况和治疗偏好对于导管内 papillary 粘菌性新生体
Dominic Amara1, Acacia R Sharma2, D Brock Hewitt2
1Department of Surgery, University of California Los Angeles, Los Angeles, California.
The Journal of surgical research
|September 17, 2024
概括
大多数患有胰腺导管内 papillary 粘膜瘤 (IPMNs) 的患者更喜欢监测而不是手术. 对IPMN的治疗决定取决于个人的癌症风险感知和焦虑水平.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 决策科学 决策科学 决策科学
背景情况:
- 导管内 papillary 粘膜瘤 (IPMNs) 是常见的前恶性胰腺病变,经常偶然发现.
- 对IPMNs的管理决策涉及手术与监视的不确定性.
- 患者的偏好和影响这些决定的心理因素尚未得到充分理解.
研究的目的:
- 描述患者对IPMN管理的偏好 (手术与监测).
- 检查治疗偏好和患者的不确定性概况之间的关联,包括风险感知,风险态度和不确定性容忍度.
主要方法:
- 进行了一项横截面调查,对来自国家选择参与小组的520名参与者进行了调查.
- 参与者模拟了一个偶然发现的IPMN与5%的癌症风险的遭遇.
- 验证的措施评估了癌症风险感知,风险态度,不确定性耐受性和治疗偏好;多变量回归分析了预测因素.
主要成果:
- 大多数参与者 (64%) 偏爱监视而不是手术 (36%).
- 增加癌症风险感知显著预测了对手术的偏好.
- 治疗偏好与风险态度或不确定性耐受性没有显著联系,但风险感知与不确定性耐受性和癌症焦虑相关.
结论:
- 患者对IPMN管理的偏好是多样化的,并受到癌症风险感知的影响.
- 癌症风险感知与不确定性耐受性和焦虑程度密切相关.
- 应考虑IPMN治疗决定是偏好敏感的,考虑到个体患者的因素.
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