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Updated: Jun 12, 2025

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells
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动态化驱动自克林和副克林TGF-β信号

Mingliang Jin1, Robert I Seed2, Guoqing Cai2

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF), San Francisco, CA, USA.

Cell
|September 17, 2024
PubMed
概括

转化生长因子-β (TGF-β) 可以在不释放其潜伏复合体的情况下发出信号. 这一发现挑战了现有的模型,并解释了特异性的TGF-β3功能,影响了免疫和发育研究.

关键词:
TGF-b信号传输TGF-b1 的使用其他:激活方式自克林信号其他: avb8整体动态化的重新分配其他类型延迟时间偏信号传递监管T细胞单颗粒冷电磁体

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