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相关概念视频

Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

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Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
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相关实验视频

Updated: Jun 12, 2025

Guided Protocol for Fecal Microbial Characterization by 16S rRNA-Amplicon Sequencing
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病理学家在实施临床微生物组诊断测试时面临的挑战

Yulia Gerasimova1, Haroon Ali2, Urooba Nadeem3

  • 1Department of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA.

The journal of pathology. Clinical research
|September 17, 2024
PubMed
概括
此摘要是机器生成的。

临床微生物组测试对慢性疾病有希望,但面临实施障碍. 本综述概述了临床病理实验室样本处理,方法,解释和监管方面的挑战.

关键词:
微生物组是一个微生物组.微生物组测试是微生物组的测试.病理学家 病理学家 病理学家病理学家和微生物组.

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科学领域:

  • 微生物学 微生物学
  • 临床病理学 临床病理学
  • 疾病的病原发生 疾病的病原发生

背景情况:

  • 人类微生物组越来越多地涉及慢性疾病,包括癌症.
  • 医疗保健专业人员和公众对临床微生物组测试越来越感兴趣.
  • 尽管微生物检测技术取得了进展,但临床采用仍然有限.

研究的目的:

  • 概述阻碍在临床病理学中实施微生物组测试的挑战.
  • 讨论可能的解决方案,以促进微生物组测试融入常规临床实践.

主要方法:

  • 审查临床微生物组测试当前的挑战.
  • 讨论影响样本处理和结果的预分析和分析因素.
  • 分析与测试方法选择,参考范围建立,数据解释和临床实用性相关的问题.
  • 考虑监管和成本因素.

主要成果:

  • 在分析前和分析样本处理方面存在重大挑战,影响测试可靠性.
  • 为特定的临床环境选择合适的测试方法是复杂的.
  • 建立可靠的参考范围和解释复杂的微生物组数据用于患者护理决策是主要障碍.
  • 监管部门的批准和成本效益是临床广泛采用的关键障碍.

结论:

  • 解决样本处理,标准化,数据解释和监管方面的挑战对于临床微生物组测试至关重要.
  • 提出了潜在的解决方案,以加快微生物组测试在临床病理学实验室的整合.
  • 成功实施可以提高对微生物组相关疾病的诊断能力和患者护理.