在药物流行病学研究中衡量社会经济不平等的挑战
Christopher Prener1, Katharina Schley2, Amanda Miles1
1Chief Medical Affairs Office, Pfizer, Inc., New York, NY, United States.
American journal of epidemiology
|September 17, 2024
概括
在药物流行病学中测量社会经济地位 (SES) 是一个挑战,实际数据. 建议包括收集患者报告的数据,并使用先进的空间分析来更好地研究健康差异.
科学领域:
- 药学流行病学 药学流行病学
- 健康差距 研究 研究 研究 研究
- 健康的社会决定因素
背景情况:
- 社会经济地位 (SES) 显著导致健康差异.
- 由于患者报告的信息有限,在追溯的真实世界临床数据中测量SES是很困难的.
- 现有的个人层面 (收入,教育) 和社区层面 (社会脆弱性指数) 的SES测量在现实数据应用方面存在局限性.
研究的目的:
- 通过使用现实世界的数据,在药物流行病学研究中解决衡量社会经济地位 (SES) 的挑战.
- 提出可行的建议,以改善药物流行病学中的SES测量.
- 加强在现实研究中对SES对健康结果的影响的审问.
主要方法:
- 审查健康研究中现有的社会经济地位 (SES) 测量方法.
- 对将当前SES指标应用于回顾性,现实世界的临床数据集的挑战进行分析.
- 根据发现的局限性和潜在解决方案,制定建议.
主要成果:
- 当前的现实世界数据往往缺乏足够的患者报告的社会经济地位 (SES) 指标.
- 在社区层面的SES措施中依赖地理代理,如邮政编码,可能是不准确的.
- 现有的方法对准确评估SES对健康结果的影响构成障碍.
结论:
- 药物流行病学需要加强衡量社会经济地位 (SES) 的方法,以准确评估健康差异.
- 建议包括增加患者报告数据的收集,以及更好地利用地理空间和人口专业知识.
- 采用这些策略将提高在现实研究中研究SES效应的能力.
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