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相关概念视频

Circadian Rhythms and Gene Regulation02:19

Circadian Rhythms and Gene Regulation

4.0K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
4.0K
Factors Affecting Body Temperature01:28

Factors Affecting Body Temperature

3.9K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may  include:
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Body Temperature01:07

Body Temperature

264
Body temperature reflects the equilibrium between heat production and heat loss within the body. Most heat is generated by metabolically active tissues, particularly the liver, heart, brain, kidneys, and endocrine organs. At rest, skeletal muscles contribute 20–30% of total heat production, but during vigorous exercise, this can increase up to 30–40 times.
The average body temperature is approximately 37°C (98.6°F) and typically ranges from 36.1–37.2°C...
264
Thermoregulation01:26

Thermoregulation

919
The human body has a sophisticated thermoregulation system that employs negative feedback mechanisms to maintain an optimal core temperature. When the core temperature drops, peripheral and central thermoreceptors send signals to the hypothalamus, activating the heat-promoting center. This center triggers several responses aimed at increasing the core temperature. First, vasoconstriction reduces the flow of warm blood from internal organs to the skin so that the heat is not lost from the skin,...
919
Equipments Used to Measure Body Temperature01:13

Equipments Used to Measure Body Temperature

978
Body temperature can be assessed using various devices and measured in Celsius or Fahrenheit.
Glass-bulb Thermometer:
Glass-bulb thermometers are hollow glass tubes with a bulb tip containing liquid such as ethanol or mercury. Historically, glass bulb mercury thermometers were the standard device to measure body temperature. Today, mercury thermometers are prohibited in many countries due to the hazardous effects of mercury and the risk of exposure if the glass bulb breaks. In general,...
978
What is Homeostasis?01:16

What is Homeostasis?

36.8K
Maintaining homeostasis requires that the body continuously maintain its internal conditions. Each physiological condition has a particular set point, from body temperature to blood pressure to levels of certain nutrients. A set point is the physiological value around which the normal range fluctuates. A normal range is a restricted set of values that is optimally healthful and stable. For example, the set point for normal human body temperature is approximately 37°C (98.6°F).
36.8K

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相关实验视频

Updated: Jun 12, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
06:53

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

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循环时钟和身体温度

Takahito Miyake1, Yuichi Inoue1, Yota Maekawa1

  • 1Department of Systems Biology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

Advances in experimental medicine and biology
|September 17, 2024
PubMed
概括
此摘要是机器生成的。

身体温度节律对能量平衡至关重要,并由昼夜时钟调节. 分子机制,包括热冲击因子和素受体,同步动物的体温周期.

关键词:
身体温度 身体温度卡尔克尔 (Calcr Calcr) 是一个计算器.循环节的时钟是循环节的时间.时钟基因是指时间基因.这是SCNSCN.

更多相关视频

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
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Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

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Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in Drosophila
09:09

Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in Drosophila

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相关实验视频

Last Updated: Jun 12, 2025

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
06:53

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

8.3K
Human Circadian Phenotyping and Diurnal Performance Testing in the Real World
10:16

Human Circadian Phenotyping and Diurnal Performance Testing in the Real World

Published on: April 7, 2020

8.5K
Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in Drosophila
09:09

Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in Drosophila

Published on: January 13, 2014

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科学领域:

  • 时间生物学 时间生物学
  • 生理学 生理学 生理学
  • 分子生物学分子生物学

背景情况:

  • 循环节律控制着每天的生理周期,身体温度波动是关键输出.
  • 这种每天的温度波动 (1-3°C) 会同步外围时钟,并保持能量恒温.
  • 热诱导涉及诸如热冲击转录因子和冷诱导型RNA结合蛋白等影响时钟基因表达的因素.

研究的目的:

  • 审查昼夜时钟机制与体温调节之间的复杂关系.
  • 为了突出涉及跨物种温度调节的保存分子通路.
  • 综合当前关于人体温度如何影响和受到昼夜系统影响的知识.

主要方法:

  • 关于昼夜节律和体温研究的文献综述.
  • 在昼夜时钟中进行热引入的基础分子机制的分析.
  • 在不同的动物模型 (poikilotherms,,小鼠) 中对温度调节和时钟基因表达进行比较分析.

主要成果:

  • 身体温度表现出稳定的昼夜振荡,这对能量平衡至关重要.
  • 特定的分子参与者,包括热冲击转录因子,冷诱导性RNA结合蛋白和托受体,调解热诱导.
  • 保存的分子电路,特别是涉及时钟神经元中的素受体,调节和小鼠的体温节律.

结论:

  • 身体温度调节和生理节律时钟深深地相互关联,相互影响.
  • 了解这些关系是理解生理同步和能量平衡的关键.
  • 共同的分子路径强调了昼夜温度调节的进化重要性.