探索活微生物摄入量与成人肥胖患病率之间的关系
Yuting Chen1, Haixiang Ni1, Hong Zhang2
1Department of Endocrinology and Metabolism, The First Affiliated Hospital of Zhejiang Chinese Medical University, No.54, Youdian Road, Shangcheng District, Hangzhou, 310009, Zhejiang, China.
Scientific reports
|September 17, 2024
概括
较高的活微生物摄入量与较低的体重指数 (BMI) 和腰围 (WC) 有关. 这表明饮食中的活微生物可能在减少成年人肥胖和腹部肥胖患病率方面发挥作用.
科学领域:
- 微生物组研究的研究.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 肥胖是一个重大的全球健康问题.
- 饮食微生物在肥胖中的作用是一个新兴的研究领域.
- 了解活微生物消费对肥胖的影响至关重要.
研究的目的:
- 调查饮食中的活微生物摄入量与成年人肥胖之间的关联.
- 分析活微生物消费与体重指数 (BMI) 和腰围 (WC) 之间的关系.
- 检查活微生物摄入量与肥胖和腹部肥胖的患病率之间的相关性.
主要方法:
- 使用了来自国家健康和营养检查调查 (NHANES) (1999-2018) 的数据.
- 将参与者分为低,中,高饮食活微生物摄入组.
- 使用线性回归,逻辑回归和受限立方线 (RCS) 曲线进行分析.
主要成果:
- 总共有42,749名参与者被分析,其中15,463人被归类为肥胖.
- 活微生物摄入量与BMI和WC的负相关性.
- 较高的活微生物摄入量与肥胖 (OR=0.812) 和腹部肥胖 (OR=0.851) 的几率降低有关.
- RCS分析证实了活微生物摄入量和肥胖指标之间的非线性负相关性.
结论:
- 饮食中的活微生物摄入量初步与成人肥胖风险降低有关.
- 研究结果表明,活微生物在减肥策略中可能发挥作用.
- 需要进一步的研究来阐明这种关联背后的机制.
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