饮食炎症指数与性结肠炎患者的疾病活性之间的关联
Zahra Bakhtiari1, Reza Mahdavi2, Kourosh Masnadi Shirazi3
1Student research committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Scientific reports
|September 17, 2024
概括
促炎症饮食与性结肠炎 (UC) 严重程度的增加有关. 采用抗炎饮食可能有助于减少UC患者的疾病活性.
科学领域:
- 胃肠病学和营养科学 胃肠病学和营养科学
背景情况:
- 饮食模式显著影响炎症标志物,可能会影响性结肠炎 (UC) 的病程.
- 了解饮食和UC活动之间的关系对于临床管理至关重要.
研究的目的:
- 调查在被诊断患有性结肠炎 (UC) 的患者中饮食炎症指数 (DII) 评分和疾病活性之间的关联.
主要方法:
- 一项涉及158名UC患者的横截面研究.
- 使用梅奥诊所评分来评估疾病的严重程度.
- 饮食摄入量通过食物频率问卷进行评估,DII得分是使用Shivappa等计算的. 方法. 方法. 方法.
- 使用后勤回归分析来确定DII分数四分位数与疾病严重程度之间的关联,调整为共变量.
主要成果:
- 53.8%的参与者处于缓解状态或轻度UC.
- 平均DII得分为-0.24 ± 0.66. 这一点是-0.24 ± 0.66.
- 缓解期患者的DII平均得分明显较低 (-0.34 ± 0.71),与活跃UC患者相比 (-0.1 ± 0.57;P = 0.02).
- 后勤回归表明,在调整混因素后,促炎性饮食会使严重UC的几率增加3.33倍 (OR:3.33 [95%CI:1.13,9.76];P = 0.02).
结论:
- 较高的促炎性食物摄入量和性结肠炎 (UC) 严重程度增加之间存在显著的关联.
- 临床建议应包括促进抗炎饮食,以潜在地减轻UC疾病的严重程度.
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