在糖尿病前期的成年人中,不同程度的体力活动和患2型糖尿病的风险:基于人口的队列研究
Wenchang Yang1, Yuntao Wu2, Yue Chen1
1Department of Nutrition and Food Hygiene, School of Public Health, Institute of Nutrition, Clinical Research Unit, Institute of Clinical Medicine, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
参与中度至高水平的体育活动可以显著降低患有糖尿病前期的成年人患2型糖尿病 (T2D) 的风险. 这一发现强调了运动对T2D预防的重要性.
科学领域:
- 内分泌学和新陈代谢学
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 糖尿病前期是发展2型糖尿病 (T2D) 的重要危险因素.
- 改变生活方式,特别是身体活动,对于管理糖尿病前期和预防T2D进展至关重要.
- 了解特定人群体体育活动和T2D风险之间的剂量反应关系对于公共卫生干预至关重要.
研究的目的:
- 调查不同程度的体力活动与2型糖尿病 (T2D) 在被诊断为糖尿病前期的中国成年人中的发病率之间的联系.
- 量化与中度和高体力活动相关的风险降低,与该队列的低活动水平相比.
主要方法:
- 一项基于人口的前性队列研究,涉及12424名患有糖尿病前期的中国成年人.
- 使用国际体力活动问卷-简单表格评估体力活动,并根据任务的代谢等价 (MET) 将其分为低,中和和高水平.
- 考克斯回归模型用于计算T2D事件的危险比率 (HRs) 和95%置信区间 (CI).
主要成果:
- 在平均3.6年的随访期间,2207名 (17.8%) 参与者患有T2D.
- 与低活动水平 (P < 0.001) 相比,中度 (HR 0.57) 和高水平 (HR 0.76) 的体育活动水平显著与降低T2D风险相关.
- 在随访期间,中度至高水平的体力活动与禁食血糖水平的降低有关,而高活动的益处在没有代谢综合征的个体中更为明显.
结论:
- 适度和高水平的体力活动与糖尿病前期的成年人患2型糖尿病的风险明显降低.
- 身体活动干预措施可能是预防糖尿病前期患者T2D的关键策略.
- 这些发现强调了促进定期体育活动对于中国人口糖尿病预防的重要性.
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