在患有支气管炎的患者中使用前素的医院变化和时间趋势
Kathryn Bakkum1,2, Jonathan Pelletier3,2, Prabi Rajbhandari1,4,2
1Divisions of Hospital Medicine.
Hospital pediatrics
|September 18, 2024
概括
从2016年到2022年,支气管炎的前素 (PCT) 测试增加了14倍. 然而,PCT使用量的增加与儿科患者抗生素处方减少无关.
科学领域:
- 儿童传染病 儿童传染病
- 临床诊断 临床诊断 临床诊断
- 医疗保健经济学 医疗保健经济学
背景情况:
- 支气管炎住院费用在美国每年超过7亿美元.
- 孕素 (PCT) 测试在儿科中越来越受欢迎,显示出在各种疾病中减少抗生素使用的潜力.
- 这项研究调查了PCT在儿科支气管炎病例中的使用趋势.
研究的目的:
- 评估婴儿支气管炎的前热素 (PCT) 检测趋势.
- 确定PCT使用率的增加是否与抗生素处方或住院率的变化相关.
- 假设每年PCT检测支气管炎的增加.
主要方法:
- 通过使用儿科健康信息系统数据库进行了一项多中心,回顾性横截面研究.
- 分析了2016年至2022年间被诊断患有支气管炎的2-23个月龄的婴儿.
- 统计分析,包括基平方和威尔科克森等级总和测试,用于比较PCT测试和不进行PCT测试的遭遇,以及Spearman的rho用于趋势分析.
主要成果:
- 超过366,000例支气管炎遭遇被审查,PCT测试在1.5%的病例中进行.
- 从2016年 (0.2%) 到2022年 (2.8%) 的PCT使用量增加了14倍以上,同比大幅增加.
- 医院水平的PCT使用与入院率 (P = .42) 或抗生素管理 (P = .06) 没有显著的关联.
结论:
- 支气管炎的前素 (PCT) 测试在2016年至2022年期间大幅增加了14倍.
- PCT测试的增加与支气管炎抗菌药物处方减少无关.
- 需要进一步的研究来确定PCT在治疗儿科支气管炎中的诊断价值和临床实用性.
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