探索运动对代谢综合征的分子机制:使用CiteSpace进行的一项书目测量和可视化研究
Kang Wan1,2, Yue Jin1, Ruobing Fan1
1School of Exercise and Health, Shanghai University of Sport, Shanghai, China.
Frontiers in endocrinology
|September 18, 2024
概括
定期运动通过关键的分子通路改善胰岛素敏感性和心血管功能来对抗代谢综合征. 进一步的研究应该加强全球合作,以获得更有效的干预措施.
科学领域:
- 运动生理学 运动生理学
- 代谢障碍 代谢障碍 代谢障碍
- 图书统计学 图书统计学
背景情况:
- 代谢综合征 (MS) 构成了重大的健康挑战,需要有效的管理策略.
- 了解运动对MS的益处的分子基础对于有针对性的干预措施至关重要.
研究的目的:
- 阐明运动影响代谢综合征的分子机制.
- 通过图书统计分析,识别运动和MS研究中的研究趋势和协作模式.
主要方法:
- 科学网络核心集合 (2014-2023) 的系统文献搜索.
- 用CiteSpace对562篇符合条件的论文进行了图书统计分析和可视化.
- 识别研究模式,受欢迎的主题和新兴趋势.
主要成果:
- 运动通过逆转肥胖,减少脂质和炎症,增强胰岛素敏感性和改善心血管功能来减轻MS.
- 确定的主要分子通路包括PPAR-γ/CPT-1/MCAD信号传输,AMPK激活和氧化生产.
- 美国在研究产出方面处于领先地位;然而,全球研究合作有限.
结论:
- 通过有益的分子通路激活,中度至高强度的运动对于管理MS至关重要.
- 为未来的研究,建议加强合作和探索新的分子标.
- 运动在代谢综合征管理方面显示出显著的治疗潜力.
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