印度儿童中枢神经系统结核病的临床和诊断特征 - - 一项描述性研究
Bella Devaleenal Daniel1, Elilarasi Selladurai2, Sarath Balaji2
1ICMR - National Institute for Research in Tuberculosis, No 1, Mayor Satyamoorthy Road, Chetpet, Chennai 600031, India.
Therapeutic advances in infectious disease
|September 18, 2024
概括
儿童结核性脑膜炎 (TBM) 带来了独特的诊断挑战,年幼的儿童经常经历严重的形式. 早期发现和综合护理对于管理儿童中枢神经系统 (CNS) 结核病至关重要.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 儿科 儿科 儿科
背景情况:
- 结核性脑膜炎 (TBM) 在儿童中由于异常的临床表现而造成诊断困难.
- 中枢神经系统 (CNS) 结核病包括TBM和结核瘤,需要不同的诊断考虑.
研究的目的:
- 描述诊断为中枢神经系统结核病的儿童的基线特征,包括TBM和结核瘤.
- 确定与儿科TBM相关的关键临床,实验室和神经成像发现.
主要方法:
- 一项追溯描述性研究分析了12岁以下患有神经症状的儿童的数据.
- 诊断评估包括临床评估,实验室测试,脑脊液分析和神经成像 (MRI,CT脑).
主要成果:
- 在600名被评估的儿童中,有61人 (10%) 患有中枢神经系统结核病 (47名TBM,14名结核病).
- 神经成像显示了76% (MRI) 和77% (CT) 的TBM暗示异常.
- 脑脊液分析显示白细胞计数 (56%),蛋白质 (49%) 和葡萄糖 (47%) 的异常.
结论:
- 患有TBM的年幼儿童往往会出现更严重的疾病.
- 诊断确认可能并不总是可以实现的,需要全面的临床方法.
- 管理应该解决诸如水头和中风等并发症.
相关概念视频
Pulmonary Tuberculosis IV
134
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
134
Pulmonary Tuberculosis III
312
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
312
Pulmonary Tuberculosis II
213
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
213
Pulmonary Tuberculosis I
224
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
224
Pulmonary Tuberculosis V
172
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
172


