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Updated: Jun 12, 2025

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
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A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

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干熊胆通过调节上腺FXR来降低外围葡萄糖皮质激素水平来发挥其抗抑郁作用

Yanlin Tao1, Zikang Li1, Jinfeng Yuan2

  • 1Shanghai Key Laboratory of Compound Chinese Medicines, The Ministry of Education (MOE) Key Laboratory for Standardization of Chinese Medicines, The MOE Innovation Centre for Basic Medicine Research on Qi-Blood TCM Theories, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Brain, behavior, & immunity - health
|September 18, 2024
PubMed
概括

干熊胆 (DBB) 通过调节法尔内索伊德X受体 (FXR) 和葡萄糖皮质激素合成,显示抗抑郁作用. 这项研究表明,DBB可能是通过控制压力激素水平来治疗抑郁症的潜在疗法.

关键词:
慢性不可预测的轻度压力抑郁症 抑郁症 抑郁症干燥的熊胆 干燥的熊胆法尔内索伊德X受体的受体葡萄糖皮质类固醇是什么?

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